Venenum Targeted Libraries
VENENUM Biodesign Collection of small molecule compounds contains large diverse discovery libraries (ECLiPS libraries) as well as targeted libraries (VTLs). Both types of libraries are designed by experienced medicinal chemists to maximize the probability for lead generation.
Currently, Venenum’s chemists are synthesizing a series of VTLs aimed at disrupting interactions between proteins. While protein-protein interactions are at the core of many essential biological processes, such as transcription or cytokine signaling, the discovery of small molecule inhibitors of these interactions has been historically challenging.
The VTLs contains small molecule mimics of protein structural motifs designed to disrupt the interfaces between protein partners.
Additional VTLs are being synthesized based on lead pharmacophores shown to disrupt protein-protein interactions.
Please contact us if you are interested in purchasing our VTL’s or would like futher information.
Venenum Targeted Libraries
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Design Motif
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Number of Compounds
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Targeted Availability
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VTL011
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Protein-Protein Interaction inhibitor
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500
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Available
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VTL012
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α-helix mimic
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400
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Available
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|
VTL013
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Protein-Protein Interaction inhibitor
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500
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Available
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|
VTL014
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α-helix mimic
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500
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Q3 2011
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|
VTL015
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β-sheet mimic
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800
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Q3 2011
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|
VTL016
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Transcription Factor Modulator
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600
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Q3 2011
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