DISCOVERY IS OUR MISSION
Discovery is our mission

 

 

Leading Edge Solutions For Drug Discovery

Venenum Targeted Libraries


 

VENENUM Biodesign Collection of small molecule compounds contains large diverse discovery libraries (ECLiPS libraries) as well as targeted libraries (VTLs). Both types of libraries are designed by experienced medicinal chemists to maximize the probability for lead generation.

Currently, Venenum’s chemists are synthesizing a series of VTLs aimed at disrupting interactions between proteins. While protein-protein interactions are at the core of many essential biological processes, such as transcription or cytokine signaling, the discovery of small molecule inhibitors of these interactions has been historically challenging.

The VTLs contains small molecule mimics of protein structural motifs designed to disrupt the interfaces between protein partners.

Additional VTLs are being synthesized based on lead pharmacophores shown to disrupt protein-protein interactions.

Please contact us if you are interested in purchasing our VTL’s or would like futher information.

 

Venenum Targeted Libraries

 

 

Design Motif

Number of Compounds

Targeted Availability

VTL011

Protein-Protein Interaction inhibitor

500

Available

VTL012

α-helix mimic

400

Available

VTL013

Protein-Protein Interaction inhibitor

500

Available

VTL014

α-helix mimic

500

Q3 2011

VTL015

β-sheet mimic

800

Q3 2011

VTL016

Transcription Factor Modulator

600

Q3 2011