Publications

• Gallo-Ebert C, Francisco J, Liu HY, Draper R, Modi K, Hayward MD, Jones BK, Buiakova O, McDonough V, Nickels JT Jr.. Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. J Biol Chem. 2018 Apr 20;293(16):5956-5974. doi: 10.1074/jbc.RA117.000800. Epub 2018 Feb 28. PubMed PMID: 29491146.
• Stroke, IL, Letourneau, JJ, Miller, TE, Xu, Y, Pechik, I, Savoly, DR, Ma, L, Sturzenbecker, LJ, Sabalski, J, Stein, PD, Webb, ML, Hilbert, DW. Treatment of Clostridium difficile infection with a small molecule inhibitor of toxin UDP-glucose hydrolysis activity. Antimicrob. Agents Chemother. (2018), 62, e00107-18.
• Letourneau, JJ, Stroke, IL, Hilbert, DW, Sturzenbecker, LJ, Marinelli, BA, Quintero, JG, Sabalski, J, Ma, L, Diller, DJ, Stein, PD, Webb, ML. Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB). Bioorganic & Medicinal Chemistry Letters (2018), 28(4), 756-7.
• Berman-Booty LD, Eraslan R, Hanumegowda U, Cantor GH, Bounous DI, Janovitz EB, Jones BK, Buiakova O, Hayward M, Wee S. Systemic Loss of C-terminal Src Kinase Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice. Vet Pathol. 2018 Mar;55(2):331-340. doi: 10.1177/0300985817747330. Epub 2018 Jan 16. PubMed PMID: 29338616.
• Letourneau JJ, Stroke IL, Hilbert DW, Cole AG, Sturzenbecker LJ, Marinelli BA, Quintero JG, Sabalski J, Li Y, Ma L, Pechik I, Stein PD, Webb ML. Synthesis and SAR studies of novel benzodiazepinedione-based inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB). Bioorg Med Chem Lett. 2018 Oct 29. pii: S0960-894X(18)30849-7. PMID: 30392779.
• Hilbert DW, Schuyler JA, Adelson ME, Mordechai E, Sobel JD, Gygax SE. 2017. Gardnerella vaginalis population dynamics in bacterial vaginosis. Eur J Clin Microbiol Infect Dis. 2017 Feb 14 [Epub ahead of print] PMID: 28197729
• Ventolini G, Khandelwal N, Hutton K, Lugo J, Gygax SE, Schlabritz-Loutsevitch N. 2017. Obesity and recurrent vulvovaginal bacterial infections in women of reproductive age. Postgrad Med J. 2017 Jan 5. [Epub ahead of print] PMID: 28057837
• Villasmil ML, Gallo-Ebert C, Liu HY, Francisco J, Nickels JT Jr. 2017. A link between very long chain fatty acid elongation and mating-specific yeast cell cycle arrest. Cell Cycle. 2017 Jul 26:1-12. doi: 10.1080/15384101.2017.1329065. [Epub ahead of print]. PMID: 28745545
• Hilbert DW, Schuyler JA, Adelson ME, Mordechai E, Sobel JD, Gygax SE. 2017. Gardnerella vaginalis population dynamics in bacterial vaginosis. Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1269-1278. doi: 10.1007/s10096-017-2933-8. Epub 2017 Feb 14.
• Ventolini G, Khandelwal N, Hutton K, Lugo J, Gygax SE, Schlabritz-Loutsevitch N. 2017. Obesity and recurrent vulvovaginal bacterial infections in women of reproductive age. Postgrad Med J. 2017 May;93(1099):297. doi: 10.1136/postgradmedj-2016-134638. Epub 2017 Jan 5. PMID: 28057837
• He S, Gleason J, Fik-Rymarkiewicz E, DiFiglia A, Bharathan M, Morschauser A, Djuretic I, Xu Y, Krakovsky M, Jankovic V, Buensuceso C, Edinger J, Herzberg U, Hofgartner W, Hariri R. 2017. Human Placenta-Derived Mesenchymal Stromal-Like Cells Enhance Angiogenesis via T Cell-Dependent Reprogramming of Macrophage Differentiation. Stem Cells. 2017 Jun;35(6):1603-1613. doi: 10.1002/stem.2598. Epub 2017 Mar 14. PMID: 28233380
• Villasmil ML, Francisco J, Gallo-Ebert C, Donigan M, Liu HY, Brower M, and Nickels JT Jr. Ceramide signals for initiation of yeast mating-specific cell cycle arrest. Cell Cycle , 15(3):441-54. PMID: 26726837
• Schuyler JA, Mordechai E, Adelson ME, Sobel JD, Gygax SE, and Hilbert DW.  Identification of intrinsically metronidazole-resistant clades of Gardnerella vaginalis.  Diagn Microbiol Infect Dis., 84(1):1-3. PMID: 26514076
• Hilbert DW, Smith WL, Chadwick SG, Toner G, Mordechai E, Adelson ME, Sobel JD, and Gygax SE.  Development and validation of a highly accurate quantitative real-time PCR assay for the diagnosis of bacterial vaginosis.  J Clin Microbiol. 2016 Apr; 54(4):1017-24. Erratum in: J Clin Microbiol. 2016 Jul; 54(7):1930.
• Pusey M, Bail S, Buiakova O, Nestor M, Yang JJ, Rice LM. 2016. Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models. Tumour Biol. 2016 Sep; 37(9):11835-11842.  PMID: 27048286
• Schlabritz-Loutsevitch N, Gygax SE, Dick E Jr, Smith WL, Snider C, Hubbard G, Ventolini G. Vaginal Dysbiosis from an Evolutionary Perspective. Sci Rep. 2016 May 26; 6:26817. PMID: 27226349
• Hilbert DW, Smith WL, Paulish-Miller TE, Chadwick SG, Toner G, Mordechai E, Adelson ME, Sobel JD, and Gygax SE.  2016.  Utilization of molecular methods to identify prognostic markers for recurrent bacterial vaginosis. Diagn Microbiol Infect Dis. 2016 Oct; 86(2):231-42. PMID: 27431434
• McCourt P, Liu HY, Parker JE, Gallo-Ebert C, Donigan M, Bata A, Giordano C, Kelly SL, Nickels JT Jr. 2016. Proper Sterol Distribution Is Required for Candida albicans Hyphal Formation and Virulence.  G3 (Bethesda). 2016 Aug 31. [Epub ahead of print]  PMID: 27587298
• Stroke, IL, Ma, L, Letourneau, JJ, Cole, AG, Li, Y, Marinelli, BA, Malone, J, Paulish-Miller, T, Pechik, I, Quintero, JG, Sabalski, JE, Savoly, DR, Wang, A, Hilbert, DW, Gygax, S, Miller, DK, Stein, P, Webb, M. Miniaturized assays for RhoA inactivation through glucosylation by Clostridium difficile toxin. Society for Laboratory Automation and Screening 4th Annual Conference and Exhibition (Washington, D.C.) 7-11 February, 2015.
• Stein, P. Simple and Complex Science and Technology. Rutgers University, November 21, 2013
• Gallo-Ebert, Christina; Donigan, Melissa; Stroke, Ilana L.; Swanson, Robert N.; Manners, Melissa T.; Francisco, Jamie; Toner, Geoffrey; Gallagher, Denise; Huang, Chia-Yu; Gygax, Scott E.; Webb, Maria; Nickels, Joseph T., Jr. Novel Antifungal Drug Discovery Based On Targeting Pathways Regulating The Fungal-Conserved Upc2 Transcription Factor. Antimicrob. Agents Chemother. (2014), 58(1), 258-266.
• Beasley, JR, Huang, C-Y, Gallo-Ebert, C, Bata, A, Donigan, M, Giordano, C, Kanneganti, N, Malone, J, Sieber-McMaster, E, Nawoschik, S, O’Brien, L, Pham, Q, Severinova, E, Shi, D, Swanson, R, Tovar, K, Xu, X, Zalamea, P, Nickels, J, Stein, P., & Webb, MW. Discovery and Optimization of GPBAR1 (TGR5) Agonists. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January 2013.
• Uveges, A, Severinova, E, Gallagher, D, Kanneganti, N, McQueney, M, Swanson, R. A Robust Ultra-High-Throughput Screening Assay for DEK Binding to DNA. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013
• Stroke, IL, Sturzenbecker, LJ, Letourneau, JJ, Quintero, JG, Sabalski, Joan E, Marinelli, B, Pechik, I, Diller, D, Paulish-Miller, T, Hilbert, DW., Gygax, S, Stein, P, Webb, M. High throughput screening of combinatorial libraries for inhibitors of Clostridium difficile toxins. Society for Laboratory Automation and Screening 2nd Annual Conference and Exhibition (Orlando, Florida) 12-16 January, 2013.
• Webb, M. The Pivitol Role of Vertical Integration in Biotechnology. Rutgers University, November 5, 2012.
• McQueney, MS, Uveges, A, Malone, J, O’Brien, L, Cole, A, Webb, M. An Ultra High Throughput Screen of the Venenum Discovery Library for PARP-1 Inhibitors for The 17th International Inflammation Research Association Conference (Lake George, New York) 9-13 September, 2012.
• Webb, M. How to Mine Novel Biology Space with Technology Picks and Shovels. Kean University, March 12, 2012.
• 1. Stroke, IL, Hilbert, DW, Letourneau, JJ, Paulish-Miller, T, Quintero, JG, Sabalski, JE. Identification and Characterization of Small Molecules Targeting Clostridium difficile. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012.
• Beasley, JR, Malone, J, O’Brien, L, Huang, C, Sieber-McMaster, E, Shi, D, Xu, X, Nawoschik, S, Pham, Q, Webb, M. Discovery of GPBAR1 (TGR5) Agonists from a 1536-well UHTS of the ECLiPS Compound Collection. Society for Laboratory Automation and Screening (San Diego, California) 6-8 February, 2012.
• Huang C, Zhao J, Simhadri S, Webb M, Ohlmeyer M, Zhi L. Discovery of a Novel Series of mGluR5 Antagonists. Gordon Research Conference, Medicinal Chemistry, Colby- Sawyer College, New London, NH, August 7-12, 2011.
• Swanson, RN, Stroke, IL, Manners, MT, Gallo-Ebert, C, Nickels, J. Engineering Transcription Factors for Use in Ultra-High Throughput DNA Binding Assays. 7th Annual Protein Engineering Summit (Boston, Massachusetts) 9-13 May, 2011.
• Stroke, IL, Manners, MT, Swanson, RN, Dimitrov, D, Gallo-Ebert, C, Nickels, J. Targeting the Transcription Factor Upc2 for Antifungal Drug Discovery. Society for Biomolecular Sciences Annual Meeting (Orlando, Florida) 16-31 March, 2011.
• Kruijf PD, Lim HD, Roumen L, Renjaan VA, Zhao J, Webb ML, Auld DS, Wijkmans JCHM, Zaman GJR, Smit MJ, Graaf CD, Leurs R. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor. Molecular Pharmacology, 80:1108-1118, 2011.