PROTEIN ENGINEERING AND PRODUCTION, CELLULAR REAGENT GENERATION

Drug discovery process at VENENUM Biodesign involves extensive work in the area of protein engineering and production, and cellular reagent generation. Our expertise in the area allows us to offer our clients a broad spectrum of services for their most challenging platforms.

Protein Production Services:

• Gene cloning
• Mutagenesis
• Recombinant protein expression in bacterial, yeast, insect and mammalian cells
• Protein purification and refolding
• Folding and oligomerization analysis (multi-angle light scattering)
• Protein-protein interaction analysis (alpha-screen, surface plasmon resonance)
• Epitope finding (mass spectrometry)

Cellular Reagent Generation:

• Engineering of mammalian cell lines for cell and membrane based assays
• Construction of custom bacterial and yeast strains