Medicinal Chemistry

Our medicinal chemistry team is led by Dr. Phil Stein. We are in state-of-the-art new space in Hamilton, New Jersey. Our NJ-based team has a proven track record of advancing hits to clinical candidates both for our own in-house research projects as well as collaboration projects with leading pharmaceutical and biotechnology partners. We are seasoned professionals with an average of 10-years experience in a wide range of therapeutic areas including oncology, inflammatory, CNS, and respiratory targets. 

Our expertise includes:

• Rapid hit-to-lead optimization
• Lead optimization for in vivo efficacy
• Complex, multi-step organic synthesis
• High-throughput synthesis in solution and on solid-phase
• Structure-based design
• Library design and synthesis